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In a world where alien parasites have begun to infiltrate humanity, high school student Shinichi Izumi becomes one of the few with a unique chance at survival. When a parasite attempts to take over his body, it ends up attaching to his right hand instead, creating an uneasy symbiosis. Named Migi, this once-hostile entity now shares Shinichi's life, offering him an insider's perspective into the parasite community while they both navigate the dangers of their new existence. Together, they face the moral and physical challenges of combating other parasites, questioning what it means to be human, and protecting those they care about.